Yang Lab@ Duke Neurobiology

Drosophila learning and decision-making

Takuya Kaneko, Ann Marie Macara, Ruonan Li, Yujia Hu, Kenichi Iwasaki, Zane Dunnings, Ethan Firestone, Shawn Horvatic, Ananya Guntur, Orie T. Shafer, Chung-Hui Yang, Jie Zhou, Bing Ye (2017). Serotonergic Modulation Enables Pathway-Specific Plasticity in a Developing Sensory Circuit in Drosophila. Neuron 95(3):623-638.

Chun Hu, Meike Petersen, Nina Hoyer, Bettina Spitzweck, Federico Tenedini, Denan Wang, Alisa Gruschka, Lara S. Burchardt, Emanuela Szpotowicz, Michaela Schweizer, Ananya R. Guntur, Chung-Hui Yang, Peter Soba (2017). Sensory integration and neuromodulatory feedback facilitate Drosophila mechanonociceptive behavior. Nature Neuroscience 20(8):1085-1095.

Ulrich Stern and Chung-Hui Yang (2017). SkinnerTrax: high-throughput behavior-dependent optogenetic stimulation of Drosophila. bioRxiv 080614; DOI: 10.1101/080614.

Ananya R. Guntur*, Bin Gou*, Pengyu Gu, Ruo He, Ulrich Stern, Yang Xiang, and Chung-Hui Yang (2017; Epub 2016). H2O2-Sensitive Isoforms of Drosophila TRPA1 Act in Bitter-Sensing Gustatory Neurons to Promote Avoidance of UV During Egg-Laying. Genetics; DOI: 10.1534/genetics.116.195172.  * Equal contribution.

Bin Gou*, Edward Y. Zhu*, Ruo He, Ulrich Stern, and Chung-Hui Yang (2016). High throughput assay to examine egg-laying preferences of individual Drosophila melanogaster. J. Vis. Exp. (109): e53716.  * Equal contribution.

Ananya R. Guntur, Pengyu Gu, Kendra Takle, Jingyi Chen, Yang Xiang, and Chung-Hui Yang (2015). Drosophila TRPA1 isoforms detect UV light via photochemical production of H2O2. PNAS 112(42): E5753-E5761.

Ulrich Stern, Ruo He, and Chung-Hui Yang (2015). Analyzing animal behavior via classifying each video frame using convolutional neural networks. Scientific Reports 5, 14351.

Ulrich Stern, Edward Zhu, Ruo He, and Chung-Hui Yang (2015). Long-duration animal tracking in difficult lighting conditions. Scientific Reports 5, 10432.

Earlier version (in "correspondence" style): Ulrich Stern and Chung-Hui Yang (2014). Ctrax extensions for tracking in difficult lighting conditions. arXiv:1409.7272.

Chung-Hui Yang, Ruo He, and Ulrich Stern (2015). Behavioral and circuit basis of sucrose rejection by Drosophila females in a simple decision-making task. Journal of Neuroscience 35(4): 1396-410.

Edward Y. Zhu, Ananya R. Guntur, Ruo He, Ulrich Stern, and Chung-Hui Yang (2014). Egg-laying demand induces aversion of ultraviolet light in Drosophila females. Current Biology 24(23): 2797-804.

Bin Gou*, Ying Liu*, Ananya R. Guntur, Ulrich Stern, and Chung-Hui Yang (2014). Mechanosensitive neurons on the internal reproductive tract contribute to egg-laying-induced acetic acid attraction in Drosophila. Cell Reports 9(2): 522-30.  * Co-first author.

Ying Liu and Chung-Hui Yang (2014). Unveiling the secrets to her heart. Neuron 83(1): 3-5.

Rebecca (Chung-Hui)'s earlier publications:

Quan Yuan, Yuanquan Song, Chung-Hui Yang, Lily Y. Jan, and Yuh-Nung Jan (2014). Female contact modulates male aggression via a sexually dimorphic GABAergic circuit in Drosophila. Nature Neuroscience 17(1): 81-8.

Chung-Hui Yang*, Sebastian Rumpf*, Xiang Yang, Michael Gordon, Wei Song, Lily Y. Jan, and Yuh-Nung Jan (2009). Control of the postmating behavioral switch in Drosophila females by internal sensory neurons. Neuron 61(4): 519-26.  * Equal contribution.

Chung-Hui Yang, Priyanka Belawat, Ernst Hafen, Lily Y. Jan, and Yuh-Nung Jan (2008). Drosophila egg-laying site selection as a system to study simple decision-making processes. Science 319(5870): 1679-83.

Wesley B. Grueber, Bing Ye, Chung-Hui Yang, Susan Younger, Kelly Bordern, Lily Y. Jan, and Yuh-Nung Jan (2007). Projections of Drosophila multidendritic neurons in the central nervous system: links with peripheral dendrite morphology. Development 134(1): 55-64.

Wesley B. Grueber*, Chung-Hui Yang*, Bing Ye, and Yuh-Nung Jan (2005). The development of neuronal morphology in insects. Curr Biol. 15(17): R730-8 Review.  * Equal contribution.

Dali Ma, Chung-Hui Yang, Helen McNeill, Michael A. Simon, and Jeffrey D. Axelrod (2003). Fidelity in planar cell polarity signaling. Nature 421(6922): 543-7.

Chung-Hui Yang, Jeffrey D. Axelrod, and Michael A. Simon (2002). Regulation of Frizzled by Fat-like Cadherins during planar polarity signaling in the Drosophila compound eye. Cell 108(5): 675-88.

Chung-Hui Yang, Michael A. Simon, and Helen McNeill (1999). Mirror controls planar polarity and equator formation through repression of fringe expression and through control of cell affinities. Development 126(24): 5857-66.

Helen McNeill, Chung-Hui Yang, Michael Brodsky, Josette Ungos, and Michael A. Simon (1997). Mirror encodes a novel PBX-class homeoprotein that functions in the definition of the dorsal-ventral border in the Drosophila eye. Genes and Development 11(8): 1073-82.

Uli (Ulrich)'s earlier publications:
See Google Scholar.